CALECIM® / SOLLAGEN®

At nearly £300 for a six-week programme, Calecim’s at-home Hair Serum comes at a price. But with doctors seeing impressive results, could it be the antidote to thinning locks?

Despite often being framed as an issue that only affects men, about one third of women experience hair loss at some point in their lives — some showing the signs as early as their thirties. Causes of female hair loss vary greatly and range from perimenopause and menopause to stress, thyroid issues, iron deficiency and, now, the rise in GLP-1 weight-loss drugs.

Is this stem cell serum the secret to great hair?

CALECIM Professionals’ unique ethically sourced red deer cord-lining stem cell technology is the latest advance in post-procedure skincare.

CALECIM Professional is the world’s only skincare powered by ethically sourced red deer cord-lining stem cells, designed to regenerate skin and aid in post-procedure recovery and results.

The technology used to create the CALECIM Professional product range is the result of 10 years of cutting edge research by Cell Research Corp, a Singapore based bio tech company. Scientists from Cell Research Corp isolated two types of stem cell strains, epithelial and mesenchymal, ethically sourced from the umbilical cord lining membrane of red deer in New Zealand. Both stem cell strains actively produce proteins when they are grown in culture media. The protein mix in culture media is called Rejuvenating Conditioned Media which helps skin cells appear more youthful.

All four products in the professional-only range contain this patented protein mix. The extract consists of a mixture, in specific proportions, of cytokines, growth factors, extracellular matrix proteins, amino acids, peptides and other proteins. They represent the full complement of proteins that are generated by the umbilical cord lining mesenchymal stem cells. These stem cells have the potential to increase epidermal cell turnover, reduce the appearance of pigmentation, fines lines and redness, and improve skin elasticity.

Enhance procedures & optimise results with Calecim Professional

Skin Regeneration Solution ‘CALECIM’ Draws Attention with Clinical Results at Guangdong Hair Medicine Conference in China

 Clear improvements in thickness and density for post-chemotherapy hair weakening cases
 Presented by Professor Kim Ji-seok of FUE ASIA, a hair transplant expert
"CALECIM-RF" combination therapy shows higher satisfaction compared to existing procedures for post-chemo hair loss improvement

Professor Kim Ji-seok presenting CALECIM clinical results at the Guangdong Hair Medicine Conference in China. Provided by Keynstone.

Skin Regeneration Solution ‘CALECIM’ Draws Attention with Clinical Results at Guangdong Hair Medicine Conference in China

US Billionaire Celebrity ‘Kim Kardashian’ Makes Surprise Visit to Korea… Buzz Surrounds Her Visit to Skin Regeneration Clinic

Kardashian sisters visit a Korean clinic famous for skin regeneration
Procedure photos shared on Instagram to 350 million followers

Director Choi Jun-ho of Hoan Clinic performing a procedure using the skin regeneration solution ‘CALECIM Derma.’ Photo = Keynstone

US Billionaire Celebrity ‘Kim Kardashian’ Makes Surprise Visit to Korea… Buzz Surrounds Her Visit to Skin Regeneration Clinic

‘Ms. Kim’ Kim Kardashian Falls for K-Beauty… Shares Photo from Hannam-dong Dermatology Clinic

The Kardashian sisters. Kim Kardashian's Instagram account

Global influencer and American TV personality Kim Kardashian and her sister visited a dermatology clinic in Seoul.

‘Ms. Kim’ Kim Kardashian Falls for K-Beauty… Shares Photo from Hannam-dong Dermatology Clinic

CellResearch and Cheongdam U Plastic Surgery Center to Conduct Joint Clinical Trial for Hair Loss & Skin Regeneration Solution ‘CALECIM’

CALECIM to be applied to ‘CDU COMPLETE,’ a post-procedure recovery system
Research Director Ivor Lim: "Korea is one of the countries with the most advanced plastic surgery technology."

CellResearch and Cheongdam U Plastic Surgery Center to Conduct Joint Clinical Trial for Hair Loss & Skin Regeneration Solution ‘CALECIM’

CellResearch and Hoan Clinic Jointly Develop Slow-Aging Exosome Solution

CellResearch Corp announced on the 5th that it is partnering with 'Hoan Clinic' in Hannam-dong to develop a slow-aging solution that integrates its skin regeneration solution, 'CALECIM Derma,' with the 'Hoan Celix Package.'

CellResearch and Hoan Clinic Jointly Develop Slow-Aging Exosome Solution

CellResearch Founder Ivor Lim: "Transcending Treatment Limits for Hair Loss, Diabetic Foot Ulcers, and Bedsores"

Targeting intractable skin diseases with ‘Super Exosomes’… The Challenge of CellResearch
‘PTT-6’ Goes Beyond Stem Cells: Inducing Regeneration with a Complex of 3,000 Components
Following the US and Japan, Korea Opens Door to Cell Therapy… Full-scale Entry into the Domestic Market

Research Director Ivor Lim having an interview with Maeil Ilbo in Samseong-dong, Seoul. Photo = CellResearch

CellResearch Founder Ivor Lim: "Transcending Treatment Limits for Hair Loss, Diabetic Foot Ulcers, and Bedsores"

Hair Loss & Skin Regeneration Solution ‘CALECIM’ Clinical Campaign Closes in Just 3 Hours… 1,000 Hospitals Participate

Clinical campaign jointly promoted by CellResearch & Keynstone… Inquiries from hospitals for additional adoption pour in
Super-exosome based solution… Proven increase in hair count & follicle cell proliferation, drawing attention for ‘Zero’ side effects
Stem cell-based ‘CALECIM’ targets female hair loss & derma markets, signaling full-scale domestic expansion

Medical staff and hospital officials visiting the CALECIM clinical campaign booth at the Korean Academy of Laser, Dermatology and Trichology.

Hair Loss & Skin Regeneration Solution ‘CALECIM’ Clinical Campaign Closes in Just 3 Hours… 1,000 Hospitals Participate

CellResearch Announces Global Clinical Results for PTT-6 at KALDAT Conference

Research Director Ivor Lim: "Significant improvement in US Phase 1 clinical trials for diabetic foot ulcers; preparing for Phase 2"
Also developing treatment platforms for neurodegenerative diseases, arthritis, SLE, gene deficiency diseases, and targeted cancer therapy

CellResearch Research Director Ivor Lim presenting global clinical results for the super exosome 'PTT-6' at the KALDAT International Conference.

CellResearch Announces Global Clinical Results for PTT-6 at KALDAT Conference

"Significant Effects in 8 out of 10 Patients, Some with Dramatic Changes"... Clinical Results of Hair Loss Treatment Revealed

"Changing the scalp environment first"... PTT-6 based 'CALECIM' effective even for intractable hair loss
PTT-6 and RF combination therapy reduces pain and maximizes hair loss improvement effects

Professor Kim Ji-seok of the Asian Association of FUE Hair Transplant Surgeons (FUE ASIA) and Director of Mammoth Hairline Clinic announced at the '2025 Korean Academy of Laser, Dermatology and Trichology' (KALDAT) international conference, held at COEX in Seoul on the 11th, that domestic clinical trials of the stem cell super-exosome based 'CALECIM' showed improvement effects in 8 out of 10 hair loss patients, with some exhibiting dramatic changes.

According to CellResearch, 'CALECIM,' a hair loss and skin regeneration solution based on the super-exosome 'PTT-6,' is a product reported to increase dermal papilla cell proliferation by 24%, reduce scalp inflammation by 30-fold, increase the number of active follicles by 15%, and improve total hair count by 14% with standalone use alone. It has been introduced in approximately 4,500 hospitals and clinics across more than 40 countries worldwide.

Director Kim Ji-seok emphasized, "In the pilot clinical trial using CALECIM, we confirmed significant clinical responses in intractable hair loss patients through a new treatment mechanism different from existing methods." He added, "It demonstrated new possibilities for hair loss treatment in patients unresponsive to existing therapies, and we expect the paradigm of hair loss treatment to shift significantly in the future."

This clinical trial was conducted on 10 hair loss patients (5 males, 5 females, average age 40). The procedure involved a combination of Radio Frequency (RF) treatment and the PTT-6 complex. Each patient received applications of PTT-6 (2.5ml–5ml) following RF laser treatment three times at one-month intervals, and progress was observed for approximately two months after the procedures. As a result, visible improvement responses appeared in 8 patients, and among them, significant changes were confirmed, including an increase of over 10% in hair diameter and follicle density.

"Significant Effects in 8 out of 10 Patients, Some with Dramatic Changes"... Clinical Results of Hair Loss Treatment Revealed

CellResearch Unveils Stem Cell Technology in Korea for the First Time

CellResearch Research Director Ivor Lim presenting at the '2024 Asia-Pacific Anti-Aging Conference'. Photo provided by CellResearch

Dr. Ivor J. Lim, Chief Scientific Officer (CSO) of CellResearch, unveiled the company’s umbilical cord lining stem cell technology for the first time in Korea through a main keynote address at the '2024 Asia-Pacific Anti-Aging Conference' (APAAC 2024) held at EXCO in Daegu.

CellResearch Unveils Stem Cell Technology in Korea for the First Time

CellResearch Super Exosome ‘PTT-6’ Lands in Korea... Caring for Hair Loss, Skin, and Wound Regeneration

Superior purity, content, and composition compared to existing stem cell sources... Optimal extraction purity and yield
‘Large-scale Clinical Campaign’ for medical staff to be held at the conference... ‘CALECIM’ also unveiled for the first time

CellResearch Super Exosome ‘PTT-6’ Lands in Korea... Caring for Hair Loss, Skin, and Wound Regeneration